Ann. Méd. Vét., 2002, 146 (2), pp 71 - 83 Potential influence of pregnancy hormones and proteins synthesized during pregnancy on the maternal immunological statusSOUSA N.M., FIGUEIREDO J.R., EL AMIRI B., BANGA-MBOKO H., BECKERS J.F.Abstract :
During pregnancy, the endocrine function of the gonads and the foeto-placental unit involves the synthesis of several hormones (progesterone, oestrogens, cortisol, prostaglandins, prolactin, chorionic gonadotropin, placental lactogen, also designed "chorionic somatomammotropin", etc.), and a series of growth factors and proteins. Some proteins and glycoproteins synthesized during gestation interfere with the establishment of pregnancy, corpus luteum maintenance, intermediate maternal metabolism, fetal growth, mammary growth and immunotolerance of the conceptus by the mother. This review includes a presentation of the main pregnancy-related hormones and proteins and their hypothetical role on the immunological status of the mother. Get the PDF Contact person : jfbeckers@ulg.ac.be |