Ann. Méd. Vét., 2008, 152 (3), pp 152-179 Actinobacillus pleuropneumoniae :
pathogenesis, diagnostic, treatment and prophylaxyVANDEN BERGH P., ZECCHINON L., FETT T., DESMECHT D.Abstract :
Porcine pleuropneumonia caused
by Actinobacillus pleuropneumoniae is a frequent and
highly infectious disease generating
significant economic losses related to deficiency in zootechnical profits and intensive use of antibiotics. The purpose of this review is to describe the various stages of pathogenesis: colonisation of the host respiratory
tract, deterioration of respiratory
clearance mechanisms, initiation and exacerbated amplification of the inflammatory reaction which plays a central role in the development of the pulmonary lesions. The clinical signs, and the macroscopic and microscopic
lesions associated to the various pleuropneumonia forms are pointed out and the recent diagnostic, medical and prophylactic advances are approached. Get the PDF Contact person : daniel.desmecht@ulg.ac.be |