Ann. Méd. Vét., 2006, 150 (1), pp 1-26 The bovine mastitis : from initiation to resolutionBOUTET P., BUREAU F., LEKEUX P.Abstract :
The cure of a cow suffering from a bacterial mastitis relies on the balance between the eradication of the pathogen and the resolution of the inflammatory response, two processes that are essential to come back to a normal milk composition with low somatic cell count. The persistence of the inflammatory response, which main consequence is a reduction in milk yield, is a feature of chronic mastitis.
This frequent disease depends on inappropriate host-pathogen interactions and is not yet well understood. This review resumes the main defence mechanisms
of the bovine mammary gland, emphasizing the predominant roles played by the neutrophil, and brings some precisions on
lipoxin implications in the resolution
of inflammation. Reasons that may explain the persistence of the inflammatory reaction, a phenomenon found in the
Staphylococcus aureus chronic mastitis, are also discussed. Get the PDF Contact person : philippe.boutet@ulg.ac.be |