Ann. Méd. Vét., 2005, 149 (2), pp 117-131 Blood transport and hepatic metabolism of fatty acids in ruminants
CUVELIER C., CABARAUX J.-F., DUFRASNE I., ISTASSE L., HORNICK J.-L.Abstract :
Blood transport and hepatic metabolism of fatty acids in ruminants present several particularities.
The plasma profile is characterized by a very small proportion of triacylglycerols-rich lipoproteins— chylomicrons and very low density lipoproteins — and a very high proportion of high density lipoproteins, which can reach 80 % of the total lipoproteins. This distribution is concomitant with a low triacylglycerol and non esterified fatty acids plasma content, but with very high esterified cholesterol and phospholipid contents.
Futhermore, the ruminant is characterized by the secretion of the majority of very low density lipoproteins at intestinal level and by a very low hepatic capacity to export triacylglycerols in these lipoproteins ; ruminant is therefore more sensible to steatosis.
Moreover, the intrahepatic lipogenesis of ruminant is reduced, with as results a dependence on fatty acids blood import, the fatty acids being then directed to one of the two major pathways of intrahepatic metabolism, oxidation or esterification into triacylglycerols. Get the PDF Contact person : ccuvelier@ulg.ac.be |